According to the Credit Suisse Research Institute’s 2013 study “Sugar: Consumption at a Crossroads,” as much as 40 percent of US healthcare expenditures are for diseases
directly related to the over consumption of sugar.
Incredibly, we spend more than $1 trillion each year fighting the damaging health effects of sugar, which runs the gamut from obesity and diabetes, to heart disease and cancer.
The fact that sugar and obesity are linked to an increased risk of cancer is now becoming well-recognized. According to a report on the global cancer burden, published in 2014, obesity is responsible for an estimated 500,000 cancer cases worldwide each year.
Nearly two-thirds of obesity-related cancers — which include colon, rectum, ovary, and womb cancers — occur in North America and Europe. A more recent British report estimates obesity may result in an additional 670,000 cancer cases in the UK alone over the next 20 years.
According to BBC News, the Cancer Research UK and the UK Health Forum report are calling for a ban on junk food ads aired before 9pm to address out of control rise in obesity and obesity-related diseases.
Meanwhile, a German investigation into diet-induced diseases and related treatment costs reveal that sugar-induced oral disease represents the greatest chunk of that nation’s health care costs.
How Excess Sugar and Obesity Promotes Cancer
One of the key mechanisms by which sugar promotes cancer and other chronic disease is through mitochondrial dysfunction.
Since sugar is not our ideal fuel, it burns dirty with far more reactive oxygen species than fat, which generates far more free radicals which in turn causes mitochondrial and nuclear DNA damage along with cell membrane and protein impairment.
Research has also shown that chronic overeating in general has a similar effect. Most people who overeat also tend to eat a lot of sugar-laden foods — a double-whammy in terms of cancer risk.
Chronic overeating places stress on the endoplasmic reticulum (ER), the membranous network found inside the mitochondria of your cells. When the ER receives more nutrients than it can process, it signals the cell to dampen the sensitivity of the insulin receptors on the surface of the cell.
Thus continuously eating more than your body really needs promotes insulin resistance by the mere fact that your cells are stressed by the work placed on them by the excess nutrients. Insulin resistance in turn is at the heart of most chronic disease, including cancer.
High-Fructose Corn Syrup Primary Culprit in Cancer
This also helps explain why intermittent fasting (as well as other forms of calorie restriction) is so effective for reversing insulin resistance, reducing your risk of cancer, and increasing longevity.
Obesity, caused by a combination of eating too much refinedfructose/sugarand rarely if ever fasting, may also promote cancer via other mechanisms, including chronic inflammation and elevated production of certain hormones, such as estrogen, which is associated with an increased risk for breast cancer.
According to recent research, from the University of Texas MD Anderson Cancer Center, refined sugar not only significantly increases your risk of breast cancer, it also raises your risk of tumors spreading to other organs.
Moreover, this study found that it was primarily the refined fructose in high-fructose corn syrup, found in most processed foods and beverages that was responsible for the breast tumors and the metastasis.
Without Sugar, Cancer Cannot Thrive
One of the most powerful strategies I know of to avoid and/or treat cancer is to starve the cancer cells by depriving them of their food source, which is primarily sugar and excessive protein.
Unlike all the other cells in your body, which can burn carbs or fat for fuel, cancer cells have lost that metabolic flexibility and can only thrive if there enough sugar present.
German cancer researcher Dr. Otto Warburg was actually given a Nobel Prize in 1931 for discovering this. Sadly very few experts have embraced his metabolic theory of cancer, but have embraced the nuclear genetic theory that is a downstream side effect of mitochondrial dysfunction.
Make no mistake about it, the FIRST thing you want to do if you want to avoid or treat cancer if you have insulin or leptin resistance (which 85 percent of people do) is to cut out all forms of sugar/fructose and grain carbs from your diet, in order to optimize the signaling pathways that contribute to malignant transformation.
Reduce Your Fructose and Non-Fiber Carb Intake
I recommend reducing your total fructose intake to a maximum of 25 grams/day, from all sources, including fruit. If you are insulin resistant, you’d do well to make your upper limit 15 grams/day.
Cancer patients would likely be best served by even stricter limits. For a more detailed discussion please review my interview with Professor Thomas Seyfried, who is one of the leading cancer pioneer researchers in promoting how to treat cancer nutritionally. I personally believe that most would benefit from reducing all non-fiber carbs (total carbs minus fiber), not just fructose, to less than 100 grams per day.
As I’ve discussed before, the risks of eating too much protein include an increased risk for cancer, as it can have a stimulating effect on the mTOR pathway, which plays an important role in many diseases, including cancer.
When you reduce protein to just what your body needs, mTOR remains inhibited, which helps minimize your chances of cancer growth. As a general rule, I recommend limiting your protein to one-half gram of protein per pound of lean body mass, which for most people amounts to 40 to 70 grams of protein a day.
By reducing people’s weight even slightly, an estimated 274,000 to 309,000 cases of type 2 diabetes could be prevented over the following two decades. Still, when you consider that the sugar and corn industries are fighting to receive the largest subsidies and market share to give you cancer, it would make sense to stop subsidizing sugar and corn before you start taxing sugary products.
Cancer Screening Does Not Save Lives
Cancer screening is conventionally touted as being an important part of “cancer prevention,” even though it does no such thing. Now, researchers question the validity of public service announcements claiming that “cancer screening saves lives.” According to a recent analysis, it’s “unclear” whether screening actually saves lives, and the researchers warn that claiming it does is “misleading.”
The same goes for breast cancer screening and colorectal cancer screening:
60 percent of women who undergo regular mammography screening for 10 years receive a false positive at some point, leading to unnecessary distress and treatment, which can have serious side effects. Studies have also shown that routine mammograms have no effect on death rates.
A study looking at colorectal cancer screening found 128 cancer deaths among every 10,000 people who received screening, compared to 192 cancer deaths among every 10,000 individuals who didn’t get screened.
While there were fewer cancer deaths among those screened, this link completely disappeared when they looked at all-cause mortality. When death from all causes was included, there was no meaningful difference between the two groups.
It’s Time to Change the Discussion About Cancer Screening
And, that as many as 10 women out of 1,000 women screened will undergo unnecessary breast removal as a result of a false positive.
Presented with such data, patients would be better able to make a personal decision about whether or not screening in their particular instance might be worth the risk. She also notes that while some may benefit from screening, doctors should not overstate the value of the tests. In an email to Reuters, Gigerenzer says:
Cancer Prevention Begins with Your Lifestyle Choices
Cancer screening is portrayed as the best form of “prevention” you can get against various forms of cancer. But early diagnosis is not the same as prevention. And cancer screening that does more harm than good can hardly qualify as the best you can hope for … I believe the vast majority of all cancers could be prevented by strictly applying basic, common-sense healthy lifestyle strategies.